Vivid Dx TECHNOLOGY
Creating a New Standard in Sepsis and AMR Diagnostics
Vivid Dx is developing a precision diagnostic platform that combines single-cell Raman spectroscopy, a scalable Raman spectra database, and advanced AI to deliver rapid, accurate, direct-from-blood results — designed to disrupt the multibillion-dollar blood culture-based diagnostic sector.
Our system delivers:
Broad pathogen ID in 30 minutes
Phenotypic AST in 3 hours
Direct-from-blood, no blood culture required
Key Advantages of the Vivid Dx Platform
Rapid Results
30-minute ID and 3-hour AST → Enables faster, life-saving treatment decisions.
Broad Pathogen Detection
Covers a wide range of sepsis-causing bacteria → Improves diagnostic accuracy across diverse infections.Phenotypic AST
Direct measurement of antibiotic response → Delivers clinically actionable susceptibility data.Direct-from-Blood Testing
No need for blood culture → Saves 2–4 days and reduces false negatives.Scalable Raman Database
Continuously expanding pathogen library → Increases accuracy and long-term value.AI-Driven Analysis
Advanced ML models for spectral interpretation → Delivers automated, high-throughput results at scale.
What is Raman Spectroscopy?
Raman spectroscopy captures tiny changes as light interacts with the cell’s molecules. This subtle change creates a distinctive “molecular fingerprint” that shows what the cell is made of — like its proteins, DNA, and other important building blocks.
Vivid Dx pushes this frontier into real-world clinical diagnostics.
“Each Raman spectrum tells the full story of a cell — its species, its activity, and even its resistance to antibiotics.”
The Breakthrough:
Turning Noisy Light Into Diagnostic Signal
Historically, Raman signals have been too unstable and noisy for clinical use. That’s where our proprietary AI stack comes in.
We built:
Signal processing pipeline that extract biologically-relevant peaks
Deep neural encoder to learn complex features for real-time classification
Confidence function to achieve single-cell level readout
Pre-clinical results are promising:
📈 99% accurate pathogen ID
📈 92% concordance with gold-standard AST
We’re going to do what MALDI-TOF did to the industry.
MALDI-TOF reshaped clinical diagnostics by proving that a database-driven platform could scale from 20 to over 4,000 species in just a few years — adding new targets in weeks, not years, at a fraction of the cost of traditional methods like PCR or FISH. We’re taking that breakthrough even further: our technology delivers the same rapid, flexible, software-like updates, but without the need for culture. Fast, adaptable, and cost-effective, we’re setting a new benchmark for real-time detection of pathogens.
A Culture-Free AST, Built on Metabolic Activity
Vivid Dx uses Raman spectroscopy to perform phenotypic AST by measuring deuterium (D₂O) uptake—revealing the metabolic activity of individual bacterial cells instead of relying on growth signals.
Resistant cells continue to metabolize in the presence of antibiotics
Sensitive cells show suppressed or halted metabolic activity
This unique signal appears in the “silent zone” of the Raman spectrum (~2100 cm⁻¹), enabling rapid assessment of antibiotic response — in just 3 hours — without waiting days for blood culture results.
This approach delivers true phenotypic AST directly-from-blood
